3 Parts of a Nucleotide and How They Are Connected

3 Parts of a Nucleotide and How They Are Connected Nucleotides are the building blocks of the DNA and RNA used as genetic material. Nucleotides also are used for cell signaling and to transport energy throughout cells. You may be asked to name the three parts of a nucleotide and explain how they are connected or bonded to each other. Heres the answer for both DNA and RNA. Nucleotides in DNA and RNA Both deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are made up of nucleotides which consist of three parts: Nitrogenous BasePurines and pyrimidines are the two categories of nitrogenous bases. Adenine and guanine are purines. Cytosine, thymine, and uracil are pyrimidines. In DNA, the bases are adenine (A), thymine (T), guanine (G), and cytosine (C). In RNA, the bases are adenine, thymine, uracil, and cytosine,Pentose SugarIn DNA, the sugar is 2-deoxyribose. In RNA, the sugar is ribose. Both ribose and deoxyribose are 5-csrbon sugars. The carbons are numbered sequentially, to help keep track of where groups are attached. The only difference between them is that 2-deoxyribose has one less oxygen atom attached to the second carbon.Phosphate GroupA single phosphate group is PO43-. The phosphorus atom is the central atom. One atom of oxygen is connected to the 5-carbon in the sugar and to the phosphorus atom. When phosphate groups link together to form chains, as in ATP (adenosine triphosphate), the link looks like O-P-O-P-O-P-O, with two additional oxygen atom attached to each phosphorus, one on either side of the atom. ​Although DNA and RNA share some similarities, they are built from slightly different sugars, plus there is a base substitution between them. DNA uses thymine (T), while RNA uses uracil (U). Both thymine and uracil bind to adenine (A). How Are the Parts of a Nucleotide Connected or Attached? The base is attached to the primary or first carbon. The number 5 carbon of the sugar is bonded to the phosphate group. A free nucleotide may have one, two, or three phosphate groups attached as a chain to the 5-carbon of the sugar. When nucleotides connect to form DNA or RNA, the phosphate of one nucleotide attaches via a phosphodiester bond to the 3-carbon of the sugar of the next nucleotide, forming the sugar-phosphate backbone of the nucleic acid.

The Case for Rand Paul for President in 2020

The Case for Rand Paul for President in 2020 Though Rand Pauls bid for the Presidency in 2016 ended after the Iowa Caucuses, he has an opportunity to rebound in 2020. Rand Paul is the libertarian-conservative son of former Texas congressman Ron Paul who retains great appeal as an outsider candidate, the type of candidate that has been successful in Republican primaries in recent years. In his 2010 run for the US Senate, Pauls primary opponent was a hand-picked ally of US Senate Minority Leader Mitch McConnell. Though his name helped him become a US Senator, Rand Paul would have to prove himself in the years that would follow. By 2016, Paul had even managed to become a strong ally of Mitch McConnell, proving that outsiders and insiders can work together. Seizing on an Opening In the first two years of his political career, Paul was not viewed as a major player in the political world. Fellow rising stars Governor Chris Christie of New Jersey and Senator Marco Rubio of Florida received most of the attention and press and played a larger role in Mitt Romneys presidential campaign. Christie was the early favorite of the more entrenched and moderate politicians and voters, while Rubio was well-liked by everyone, but a clear favorite of the Tea Party. And then something happened: Rand Paul filibustered a nominee to bring attention to the federal governments droning program. Pauls numbers shot up immediately, and he was now gaining an audience. His libertarian-leanings made him a natural spokesperson to promote abolishing the IRS during the tea party targeting scandal and as a privacy advocate during the NSA surveillance scandal. As the Obama administration agreed to intervene in worn-torn Syria - in which that intervention could possibly once again lead to arming terrorist-supporting forces - Pauls opposition was sound. In 2013, nearly every breaking story was starting to play perfectly into Pauls political realm as Rubios ill-advised enforcement-free immigration push led to a quick erosion of conservative support. A Libertarian-Conservative Platform A Rand Paul candidacy could possibly shake up the field like no other candidate outside of, say, Sarah Palin. Paul would likely be the most fierce advocate for federalism and limited government. His states right approach on issues ranging from gay marriage to marijuana legalization is one in which the grassroots of the Republican Party is rushing to following years of being let down by big government Republicanism. Paul would be less prone to agreeing to big government programs out of fear of being attacked by the media. He would also likely have the least interventionist foreign policy of all the candidates. Foreign policy is an area where the Republican party desperately needs to have an honest talk about the United States proper role. After 8 years of what is turning into one foreign policy disaster after the next, 2016 may be the perfect time to have that debate. Too often, Republicans seem too afraid to just say not to supporting interventionist policies. The debate is needed. While Paul leans very libertarian overall, he is not a socially-liberal libertarian. He is very pro-life and has stood up for life. If anyone can make the argument that you dont have to hold Christian beliefs to realize that a life is a life, Paul might be that guy. On Economic policy, he is good on taxes, subsidies, and opposing crony capitalism. He is a strong supporter of the 2nd Amendment. He joined fellow tea party star Ted Cruz in opposing the Rubio immigration plan. Does Paul have flaws? Of course. But he is firmly entrenched on the liberty and freedom side of the GOP, perhaps more-so than any other potential candidate. Electability Which brings us to the most important question: is Rand Paul electable? While Paul became a viable US Senate candidate mostly because of who is father was, he is in many ways very different than his father. His father was never taken seriously by most observers. Whether it was his larger-than-reality personality or some of the positions he took (and the way he explained them), Ron Paul was just never a mainstream kind of candidate. Rand Paul is different on many levels. Paul is more measured in his approach. He is naturally gifted in debating points that most conservatives wouldnt touch. He knows how to pick his battles and knows how to not step into a trap. As a politician, Rand Paul is proving to be vastly superior to his father. His appeal can also be broad. He is now a grassroots conservative favorite, though he lost the battle of outsider to both Donald Trump and Ted Cruz in 2016. He has had some trouble convincing the more interventionist crowd on his foreign policy, and would need to work on that portion of his platform before launching another bid. His argument does have some appeal: We are tired of funding nations run by people who hate us; We are tired of arming rebels who wind up being more extreme than the people we wanted overthrown, and then get attacked with our own weapons. Obama ran on change in foreign policy and has been no less interventionist or check-write happy than any of his predecessors. Rand Paul needs to find the right balance on foreign policy that both adheres to his beliefs and exhibits strength and resolve when necessary. Then there is the youth factor. In 2012, Mitt Romney won with people over 30, but overwhelmingly lost the 29-and-under crowd. While Ron Paul did not have broad support, he did have a lot of support with younger people. Rand Paul has positioned himself against both the Obama Administration and entrenched Republicans like John McCain on the governments US citizen data-mining programs. Paul even threatened a class-action lawsuit with the American people over that surveillance. His libertarian and hands off view of government can actually appeal to the age brackets that overwhelmingly supported Obama, and who have gradually become disenchanted with the direction he has taken. Rand Pauls electability is enhanced because he might have the best chance of persuading the age bracket the GOP does worst with.